COX/PGE2 axis critically regulates effects of LPS on eosinophilia-associated cytokine production in nasal polyps
نویسندگان
چکیده
منابع مشابه
T helper cell population and eosinophilia in nasal polyps.
OBJECTIVE To analyze the immunological pattern of nasal polyposis in patients with and without allergy, the percentages of CD4+ cells expressing intracellular interferon-gamma and interleukin-4 (T helper [T(H)] type 1 and 2 cells) were measured by flow cytometry in samples from patients with nasal polyps. METHODS Samples from 32 patients (16 atopic, 16 nonatopic) were studied. The fresh nasal...
متن کاملCould Eosinophilia predict clinical severity in nasal polyps?
BACKGROUND Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear.Since eosinophils are the main inflammatory cells in the substantial proportion of nasal polyp tissues, they are considered potentially responsible for the etiopathogenesis and prognosis of the disease. Aim of this study was to investigate the relation between mucosal and peripheral eo...
متن کاملDistinct characteristics of nasal polyps with and without eosinophilia.
INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS NPs tissues were obtained from eighty-six NPs patients during surgery. Eosinophilic and noneosinophilic NPs were dis...
متن کاملInfluence of Allergy on Cytokine Level in Nasal Discharge of Patients with Nasal Polyps
Cytokine levels in nasal discharge reflect the inflammatory status of the nasal mucosa. The aim of the paper was to compare the concentrations of cytokines in nasal discharge in allergic and non-allergic patients with nasal polyps (NP). Thirty patients with NP (13 atopic and 17 non-atopic) were included in this study. Samples of nasal discharge were collected from nasal cavities of all 30 subje...
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ژورنال
عنوان ژورنال: Clinical & Experimental Allergy
سال: 2012
ISSN: 0954-7894
DOI: 10.1111/j.1365-2222.2012.04015.x